Rotigotine-induced nail dyschromia in a patient with Parkinson disease

Transdermal rotigotine: double-blind, placebo-controlled trial in Parkinson disease.

OBJECTIVE To assess the response to the rotigotine transdermal system (Neupro; Schwarz Pharma Ltd, Monheim, Germany), a nonergolinic dopamine agonist, in patients with early Parkinson disease. DESIGN Randomized, double-blind, multicenter, placebo-controlled study. SETTING Fifty sites in the United States and Canada. PATIENTS Two hundred seventy-seven patients with early Parkinson disease....

[Melanoma in a patient with Parkinson disease].

Overnight switch from ropinirole to transdermal rotigotine patch in patients with Parkinson disease

BACKGROUND A recent trial involving predominantly Caucasian subjects with Parkinson Disease (PD) showed switching overnight from an oral dopaminergic agonist to the rotigotine patch was well tolerated without loss of efficacy. However, no such data have been generated for Korean patients. METHODS This open-label multicenter trial investigated PD patients whose symptoms were not satisfactorily...

Non-Melanoma-Associated Dyschromia of the Proximal Nail Fold

Subungual melanoma with pigmentation beneath the nail that extends to involve the proximal nail fold is referred to as Hutchinson's sign. Black or brown subungual discoloration involving the proximal nail fold secondary to other etiologies has been referred to as pseudo-Hutchinson's sign. Three patients with nail discoloration and concurrent dyschromia of the proximal nail fold are described: a...

Upper Cervical Epidural Abscess in a Patient With Parkinson Disease

To our knowledge, there are no reports in the literature of patients with Parkinson disease (PD) developing upper cervical spine infections. Our objective is to present a case of upper cervical epidural abscess in a patient with PD and to review upper cervical spine infection. We present the patient's presentation, physical examination, imaging findings, and management as well a review of the l...